Old drug learns a new trick

Amphotericin B is one of the oldest antifungal drugs in common use (discovered in 1955)to treat serious fungal infections. It actually kills the fungus (fungicidal) rather than just stop it growing (fungistatic) so remains an important weapon in the fight against Aspergillus to this day.Conventional formulations of the drug are not absorbed well through the gut and are not easy to dissolve in

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