PEGylated Uricase in Gout
The gout demon 1799
One of the many enzymes manufactured by Aspergillus fermentation is uricase. Uricase is an enzyme that helps to remove the chemical uric acid (naturally made in a wide range of organisms during purine production). Humans do not have any uricase activity in their bodies - the gene is present but it has been switched off many years ago during our evolution.
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